23andMe: The Gift That Keeps on Giving
23andMe is a leading provider of personalized genetic testing (screen shot of product above). For $229 and a test tube of spit, anyone can have their DNA analyzed and receive direct reports on their ancestry, genetic traits, health risks and pre-dispositions, carrier risks and more. Consumers are also invited to share their genetic information with relatives and healthcare professionals and they can choose to have their “de-identified” data shared with pharmaceutical and medical research companies for the development of new drugs and treatments. About 80% of consumers agree to share their personal ...read more
The Written Word
C. Ben Mitchell, Ph.D. Distinguished Fellow The Tennessee Center for Bioethics & Culture
“A Call to Christian Academics Regarding Medical and Technological Ethics.”
Larry Locke is a Professor and Associate Dean of the McLane College of Business at the University of Mary Hardin-Baylor and a Research Fellow of LCC International University. This insightful essay issues a call for Christian academics to invest themselves in the medical ethical questions of today. “Now is the time,” he concludes, “for Christian academics and Christian ethicists to apply themselves and all their skill to these and other looming questions. Our generation has been gifted with an ...read more
What Does It Take to Alter Our Next Generation?
D. Joy Riley, M.D., M.A. Executive Director
I have been thinking about how one generation proactively alters the succeeding one. As I contemplated this conundrum, I found myself writing a story instead of a list. That story was published as a SALVO blog piece, and the link is below. The “angsty” pirate lives in a dystopia created by childhood desire, indulgent parents, a cooperative, complicit medical-industrial complex, and a legal climate in which desire is codified into law. What could possibly go wrong with that?
Click here to read the story. Then, send any comments to us through the Contact Us feature here ...read more
EctoLife: A Cautionary Tale
Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University In the December 2022 TN-CBC newsletter article entitled Déjà vu all over again, D. Joy Riley drew our attention to the parallels between the recently released YouTube video EctoLife: The world’s first artificial womb facility, and the fake publicity for the movie GATTACA 25 years ago. The new video, while actually conceptual, presents ectogenesis, the complete development of a baby in an artificial womb, as a current reality. Once again, a number of viewers were fooled. Unfortunately, it is perhaps more realistic than we dare to think. In a revealing interview by Beau Davidson with the Ectolife ...read more
GATTACA: 25 Years On
Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University
(Editor’s Note: The Tennessee Center for Bioethics & Culture screened GATTACA at the end of June at the international bioethics conference held by the Center for Bioethics & Human Dignity at Trinity International University. Dr. Shelton presented opening remarks, which, lightly edited, are presented here.)
The movie, GATTACA, is entertaining to watch as is, but is also rife with symbolism and subtle—and some not so subtle—philosophical messages. 25 years on: it has proved to be prescient in a number of ways.
GATTACA depicts a dystopian world in which there is a new type of social ...read more
Who is He and what has he done to our children?
Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University
Remember He Jiankui? He is the Chinese scientist who used CRISPR technology to edit the CCR5 gene for the HIV receptor in the genomes of human embryos. His goal was to make them HIV resistant. He reported at an international conference in 2018 that two of the edited embryos had resulted in the live births of non-identical twins, Nana and Lulu. There were also reports of a third child born in 2019. His revelations in a public forum provoked moral outrage from the scientific community. Global pressure caused Chinese authorities to suspend ...read more
23andMe and Drug Development
D. Joy Riley, M.D., M.A. Executive Director
More than a decade ago—in a different time and a different place—a neighbor offered me a box of stuff he had bought as part of a lot at some estate sale. He needed to get rid of no small amount of “stuff,” so he gave me that box of tarnished silverware and odds and ends. I took it home and spent a couple of days cleaning it. We were already planning a yard sale, and so I placed the now-cleaned items I did not need from the neighbor’s box in the sale. Imagine his surprise ...read more
Human Flourishing in an Age of Gene Editing
A Book Review By R. Henry Williams, M.D., F.A.C.P., M.A. (Ethics) Board Chairman, The Tennessee Center for Bioethics & Culture
Human Flourishing in an Age of Gene Editing Erik Parens and Josephine Johnston, Editors Oxford University Press, 2019
As we now live in a time when our genetic code can be altered, whether for better or worse, how should we think about what is best for ourselves? How can we as a human species and as individuals flourish? These are the questions posed in the new volume, Human Flourishing in an Age of Gene Editing. The essays here are interactive, frequently referencing one another, as the ...read more
A Moratorium on Heritable Human Genome Editing: Illusory or Real?
D. Joy Riley, M.D., M.A. Executive Director
In March, 2019, Nature published a commentary penned by Eric Lander, Françoise Baylis, Feng Zhang, Emmanuelle Charpentier, and Paul Berg, and signed by 13 other notables. The name of the commentary is “Adopt a moratorium on heritable genome editing.” This document requires analysis.
First, some definitions are needed. A moratorium is defined as a “suspension of activity,” or “an authorized period of delay or waiting.” Heritable means “capable of being passed from one generation to the next.” Additionally, clinical can refer to a “scientifically detached” attitude or “the observation and treatment of patients directly.” Each of ...read more
Transgenic Monkeys: Coming to a Lab Near You?
D. Joy Riley, M.D., M.A. Executive Director
The initial draft sequence of the chimpanzee genome was published in September 2005 – in comparison with the human genome. A few months later, geneticist James M. Sikela wrote in PLOS Genetics, “the genes and genetic changes that are responsible for making the human brain what it is and for allowing it to do what it uniquely does, have long been among the most prized jewels of our genome.” In that paper, Sikela considered how one could locate the changes in the genome that account for “human-specific cognitive abilities.” How could one prove that a ...read more
