EctoLife: A Cautionary Tale

 

Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University

In the December 2022 TN-CBC newsletter article entitled Déjà vu all over again, D. Joy Riley drew our attention to the parallels between the recently released YouTube video EctoLife: The world’s first artificial womb facility, and the fake publicity for the movie GATTACA 25 years ago. The new video, while actually conceptual, presents ectogenesis, the complete development of a baby in an artificial womb, as a current reality. Once again, a number of viewers were fooled. Unfortunately, it is perhaps more realistic than we dare to think. In a revealing interview by Beau Davidson with the Ectolife ...read more

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If Monkeys Could Talk

Joyce A. Shelton, Ph.D. Professor of Biology, Trinity International University Guest Column

Recent news announcements proclaimed, with both excitement and alarm, that Tan and colleagues, scientists from China and the US, had successfully produced human-monkey hybrid embryos. (1, 2) The hybrids (also termed chimeras) were made by injecting human pluripotent stem cells from an induced pluripotent stem cell line into 132 early- stage monkey embryos. Human pluripotent stem cells have the capacity to develop into a range of tissues and cell types which ultimately form all the structures of the human body including the brain and reproductive cells (sperm and egg). (3) In ...read more

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Tennessee Legislative Update: Commercial Surrogacy and a Pot of Gold

  By D. Joy Riley, M.D., M.A. Executive Director

References to pots of gold usually occur in the month of March, and involve leprechauns and rainbows. This year, pots of gold figure in at least one set of companion bills (House Bill No. 1379 and Senate Bill No. 425) the Tennessee Legislature is transforming into law. Instead of leprechauns and rainbows, though, it is the fertility physicians/clinics and “third-party reproductive care for the benefit of the enrollee(s).” The pots of gold are to be provided by “insurance companies,” which means, of course, “the insured,” which would include all of us who pay insurance ...read more

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Human Flourishing in an Age of Gene Editing

 

A Book Review By R. Henry Williams, M.D., F.A.C.P., M.A. (Ethics) Board Chairman, The Tennessee Center for Bioethics & Culture

Human Flourishing in an Age of Gene Editing Erik Parens and Josephine Johnston, Editors Oxford University Press, 2019

 

 

As we now live in a time when our genetic code can be altered, whether for better or worse, how should we think about what is best for ourselves? How can we as a human species and as individuals flourish? These are the questions posed in the new volume, Human Flourishing in an Age of Gene Editing. The essays here are interactive, frequently referencing one another, as the ...read more

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Statement on the Clinical Use of Human Germline Genome Editing

The Tennessee Center for Bioethics & Culture responds to the Public Call for Evidence for the International Commission* on the Clinical Use of Human Germline Genome Editing

 

Given that According to the canons of research on children, experiments are only ethically justified when there are clear benefits to that individual child and proportional burdens to that child. Risks and burdens beyond truly “minimal” to individual children are not justified to benefit other children. To do so is to treat one child as a means to another child’s ends (i.e., to instrumentalize that child).

 

Whereas Human germline genome editing is experimentation on embryonic humans who cannot give consent, ...read more

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A Moratorium on Heritable Human Genome Editing: Illusory or Real?

D. Joy Riley, M.D., M.A. Executive Director

In March, 2019, Nature published a commentary penned by Eric Lander, Françoise Baylis, Feng Zhang, Emmanuelle Charpentier, and Paul Berg, and signed by 13 other notables. The name of the commentary is “Adopt a moratorium on heritable genome editing.” This document requires analysis.

First, some definitions are needed. A moratorium is defined as a “suspension of activity,” or “an authorized period of delay or waiting.” Heritable means “capable of being passed from one generation to the next.” Additionally, clinical can refer to a “scientifically detached” attitude or “the observation and treatment of patients directly.” Each of ...read more

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It Has Arrived: Gene Editing Recommendations Published

D. Joy Riley, M.D., M.A. Executive Director

The committee appointed to advise our government regarding the editing of genes, including editing the genes of the human embryo, has published a draft report (see the title page screen shot above). We at The Tennessee Center for Bioethics & Culture are studying the document’s 261 pages, and have a few caveats to share with our readers. Germline gene editing was given cautious approval by the committee:

Heritable germline genome editing trials must be approached with caution, but caution does not mean they must be prohibited. (p. 102)

and

If the technical challenges are ...read more

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CRISPR — Who’s in Charge? (Part IV)

D. Joy Riley, M.D., M.A. Executive Director

This is part IV of our report. View part I, part II, or part III.

The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.

Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.

Here is a brief look at some of the writings and organizational ...read more

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CRISPR — Who’s in Charge? (Part III)

D. Joy Riley, M.D., M.A. Executive Director

This is part III of our report. View part I, part II, or part IV.

The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.

Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.

Here is a brief look at some of the writings and organizational ...read more

CRISPR — Who’s in Charge? (Part III) Read More »

CRISPR — Who’s in Charge? (Part II)

D. Joy Riley, M.D., M.A. Executive Director

This is part II of our report. View part I, part III, or part IV.

The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.

Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.

Here is a brief look at some of the writings and organizational ...read more

CRISPR — Who’s in Charge? (Part II) Read More »