23andMe: The Gift That Keeps on Giving
23andMe is a leading provider of personalized genetic testing (screen shot of product above). For $229 and a test tube of spit, anyone can have their DNA analyzed and receive direct reports on their ancestry, genetic traits, health risks and pre-dispositions, carrier risks and more. Consumers are also invited to share their genetic information with relatives and healthcare professionals and they can choose to have their “de-identified” data shared with pharmaceutical and medical research companies for the development of new drugs and treatments. About 80% of consumers agree to share their personal ...read more
GATTACA: 25 Years On
Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University
(Editor’s Note: The Tennessee Center for Bioethics & Culture screened GATTACA at the end of June at the international bioethics conference held by the Center for Bioethics & Human Dignity at Trinity International University. Dr. Shelton presented opening remarks, which, lightly edited, are presented here.)
The movie, GATTACA, is entertaining to watch as is, but is also rife with symbolism and subtle—and some not so subtle—philosophical messages. 25 years on: it has proved to be prescient in a number of ways.
GATTACA depicts a dystopian world in which there is a new type of social ...read more
23andMe and Drug Development
D. Joy Riley, M.D., M.A. Executive Director
More than a decade ago—in a different time and a different place—a neighbor offered me a box of stuff he had bought as part of a lot at some estate sale. He needed to get rid of no small amount of “stuff,” so he gave me that box of tarnished silverware and odds and ends. I took it home and spent a couple of days cleaning it. We were already planning a yard sale, and so I placed the now-cleaned items I did not need from the neighbor’s box in the sale. Imagine his surprise ...read more
Human Flourishing in an Age of Gene Editing
A Book Review By R. Henry Williams, M.D., F.A.C.P., M.A. (Ethics) Board Chairman, The Tennessee Center for Bioethics & Culture
Human Flourishing in an Age of Gene Editing Erik Parens and Josephine Johnston, Editors Oxford University Press, 2019
As we now live in a time when our genetic code can be altered, whether for better or worse, how should we think about what is best for ourselves? How can we as a human species and as individuals flourish? These are the questions posed in the new volume, Human Flourishing in an Age of Gene Editing. The essays here are interactive, frequently referencing one another, as the ...read more
Statement on the Clinical Use of Human Germline Genome Editing
Given that According to the canons of research on children, experiments are only ethically justified when there are clear benefits to that individual child and proportional burdens to that child. Risks and burdens beyond truly “minimal” to individual children are not justified to benefit other children. To do so is to treat one child as a means to another child’s ends (i.e., to instrumentalize that child).
Whereas Human germline genome editing is experimentation on embryonic humans who cannot give consent, ...read more
A Book for (Y)our Time – A Review
D. Joy Riley, M.D., M.A. Executive Director
Reading Siddhartha Mukherjee’s The Gene: An Intimate History (NY, NY: Scribner, 2016; paperback, 2017) is to take a 150+ year print journey with an English-speaking physician and scientist, who is also a renaissance man. Mukherjee, an assistant professor of medicine at Columbia University, won the Pulitzer Prize in 2011 for his non-fiction work, The Emperor of All Maladies: A Biography of Cancer. I have not read that earlier work, but have spent time delving into The Gene.
The Gene: An Intimate History begins with the author’s 2012 trip to Calcutta with his father to visit a ...read more
Biobanking
http://www.bioedge.org/index.php/bioethics/bioethics_article/8950/
