First Human Embryos Edited in U.S.: A Bright Red Line Is Crossed
D. Joy Riley, M.D., M.A. Executive Director
“Sooner than we expected”: A friend – a scientist steeped in the bioethics realm – wrote to me of her surprise at the announcement of the first embryonic humans edited in the United States. Steve Connor, writing in the MIT Technology Review, reported the work on 26 July 2017. Doubtless, the publication of the work in a scientific journal will follow.
The article, “First human embryos edited in U.S.” by Steve Connor, describes the process thusly: “A person familiar with the research says ‘many tens’ of human IVF embryos were created for the experiment using the ...read more
It Has Arrived: Gene Editing Recommendations Published
D. Joy Riley, M.D., M.A. Executive Director
The committee appointed to advise our government regarding the editing of genes, including editing the genes of the human embryo, has published a draft report (see the title page screen shot above). We at The Tennessee Center for Bioethics & Culture are studying the document’s 261 pages, and have a few caveats to share with our readers. Germline gene editing was given cautious approval by the committee:
Heritable germline genome editing trials must be approached with caution, but caution does not mean they must be prohibited. (p. 102)
and
If the technical challenges are ...read more
CRISPR — Who’s in Charge? (Part IV)
D. Joy Riley, M.D., M.A. Executive Director
This is part IV of our report. View part I, part II, or part III.
The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.
Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.
Here is a brief look at some of the writings and organizational ...read more
CRISPR — Who’s in Charge? (Part III)
D. Joy Riley, M.D., M.A. Executive Director
This is part III of our report. View part I, part II, or part IV.
The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.
Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.
Here is a brief look at some of the writings and organizational ...read more
CRISPR — Who’s in Charge? (Part II)
D. Joy Riley, M.D., M.A. Executive Director
This is part II of our report. View part I, part III, or part IV.
The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.
Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.
Here is a brief look at some of the writings and organizational ...read more
CRISPR — Who’s in Charge? (Part I)
D. Joy Riley, M.D., M.A. Executive Director
This is part I of our report. View part II, part III, or part IV.
The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.
Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers. This is part I of our report.
On 16 June 2015, ...read more
Taking stock: Where are we now?
D. Joy Riley, M.D., M.A.
Taking stock of where one is at the beginning of a new project or a new year is a good idea. Where we are in the entire realm of bioethics is beyond the scope of one blog post, but what follows are some landmarks discernible in January 2016…
Physician-Assisted SuicideOn Sunday, 24 January, John Jay Hooker, Tennessee lawyer, politician, and activist, died. Mr. Hooker had most recently championed “death with dignity” — physician-assisted suicide — in a proposed bill and in the courts. By the time of his death, neither the legislature nor the courts had provided ...read more
Gene-editing summit supports some research in human embryos — Nature News
By Sara Reardon
3 December 2015
Read here.
CRISPR: What is it? Who decides what we do with it?
D. Joy Riley, M.D., M.A.
What is it?Imagine a word processor for genes, where you could search for a defective gene, find the mutation, cut it out, and replace it with the proper DNA sequence. The cutting and replacing part of the process is what CRISPR and its associated (Cas) systems do. They are enzymes used to clip out particular sections of DNA in a cell’s nucleus, and replace the removed sections with other DNA segments, presumably replacing “defective” DNA with “good” DNA.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) were first described in 2012, and the technique was used in human ...read more