Please click an article title below to read more.

Guinea Pigs

November 10, 2021 • Posted in Blog

Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University

Successful xenotransplantation, animal donor to human recipient organ transfer, is the holy grail for medical doctors and scientists who study organ transplant. Why? Approximately 107,000 people are awaiting organ transplant in the US. Most will wait up to 2 to 3 years. About 17 people die per day because there are not enough organs available to meet the demand (1). Animal organs that have been genetically engineered to remove tissue molecules that cause transplant rejection would go a long way toward relieving the organ shortage.

A recently proclaimed major transplantation breakthrough attracted widespread ...read more

Risk versus Benefit

October 18, 2021 • Posted in Blog

Janet Liljestrand, M.D., M.A.

Whether we realize it or not, we weigh the benefit versus the risk of most decisions, large and small. When making medical decisions, physicians will sometimes refer to the risk/benefit ratio. A math problem with numbers? Unfortunately not, but a clinical judgment seeking to determine if the benefit that this particular patient is likely to receive is greater or lesser than the risks the patient will be assuming with the procedure or medication.

Childhood immunizations risks are often stated to be less than one in a million. With such a low risk, the benefits are great by comparison. ...read more

Human Dignity — A First Principle

September 20, 2021 • Posted in Blog

C. Ben Mitchell, Ph.D. Distinguished Fellow The Tennessee Center for Bioethics & Culture

After the horrific human rights abuses of Nazi Germany were revealed at the end of World War II, an international tribunal was held in Nuremberg to try those who were responsible for the Holocaust. Hard on the heels of those Nuremberg Trials (1945-46) followed the United Nations Declaration of Human Rights (1948) which enshrined the notion of human dignity, declaring that “All human beings are born free and equal in dignity and rights. They are endowed with reason and conscience and should act towards one another in a spirit of ...read more

What We’re Reading

July 17, 2021 • Posted in Blog

www.CartoonStock.com  

C. Ben Mitchell, Ph.D. Distinguished Fellow

Medically assisted deaths rose by 17% in 2020, continuing upward trend: Health Canada

By Joan Bryden The Canadian Press Posted June 8, 2021 1:01 am

I have several concerns about this situation:

For Health Canada, the government health service, to provide access to P-AS is a financial conflict of interest. Medicalized suicide should not be in the hands of those who hold the purse strings. Pain is manageable but other forms of suffering are not best treated with analgesics. True palliative care must address all forms of suffering. Medicine should not be coopted by the P-AS ...read more

If Monkeys Could Talk

May 13, 2021 • Posted in Blog

Joyce A. Shelton, Ph.D. Professor of Biology, Trinity International University Guest Column

Recent news announcements proclaimed, with both excitement and alarm, that Tan and colleagues, scientists from China and the US, had successfully produced human-monkey hybrid embryos. (1, 2) The hybrids (also termed chimeras) were made by injecting human pluripotent stem cells from an induced pluripotent stem cell line into 132 early- stage monkey embryos. Human pluripotent stem cells have the capacity to develop into a range of tissues and cell types which ultimately form all the structures of the human body including the brain and reproductive cells (sperm and egg). (3) In ...read more

A Tale of Two Data Scientists

March 25, 2021 • Posted in Blog

 

Neil Ferguson, Ph.D. Infamous Graph Youyang Gu

 

D. Joy Riley, M.D., M.A. Executive Director

It was a long year ago (March 2020) that a dire prediction was issued by a group at Imperial College London (UK) regarding the possible effects of the novel coronavirus, SARS-CoV-2. The model predicted more than 500,000 UK deaths, and >2.2 million deaths in the U.S. by summer if no action were taken. One of the data scientists issuing that proclamation was Neil Ferguson, Ph.D. He and his group advised the government that “in the UK and US context, suppression will minimally require a combination of social distancing of the entire ...read more

Is It Science or Scientism?

February 28, 2021 • Posted in Blog

Joyce Shelton, Ph.D. Professor of Biology, Trinity International University Guest Column

In the climate of fear, uncertainty and urgency engendered by the COVID-19 pandemic, it is often difficult to know what to do or whom to trust. Public policy makers are daily making decisions and enacting rules that affect our lives and dictate our actions in the name of protection. They lend authority and justification to their decisions by claiming that they are following the science, implying that this appeal to a trusted, rational voice should be enough to calm our concerns and guarantee our compliance. But the elevation of science to the ...read more

The Ethics of Rationing COVID-19 Vaccine for the Sickest Among Us

January 13, 2021 • Posted in Blog

C. Ben Mitchell, Ph.D Distinguished Fellow

We must not allow our combined COVID-19 fatigue to prevent us from asking important questions about public health ethics. At the time I am writing this essay, we are just transitioning into Phase 2 of the vaccination plan. I am sure our public health officials are doing the best they can under unprecedented circumstances, so we should give them the benefit of the doubt. But for the sake of clarity in the future, some retrospective analysis will be crucial.

For instance, in our own state, we have abandoned traditional triage ethics in favor of a purely age-based ...read more

The Prescription for Flourishing Embodiment in Public Bioethics

December 4, 2020 • Posted in Blog

 

A Book Review

C. Ben Mitchell, Ph.D. Distinguished Fellow

American public bioethics does not have a sterling history because it misunderstands its most important subject, the human subject. This is the claim of a brilliant new book by O. Carter Snead, the Director of the de Nicola Center for Ethics and Culture and professor of Political Science at the University of Notre Dame.

In What it Means to be Human: The Case for the Body in Public Bioethics (Harvard, 2020), Snead offers a genealogy of American public bioethics. Public bioethics, as contrasted with clinical bioethics, is the realm of human subjects research where, instead ...read more

The Problem of Ill-Gotten Gain in Health Care

October 22, 2020 • Posted in Blog

C. Ben Mitchell, Ph.D. Distinguished Fellow

The politicized debate about President Trump’s treatment for Covid-19 may have shrouded an important set of questions about the science of developing treatments, viz., the problem of ill-gotten gain.

Among other treatment protocols, the President received Regeneron’s REGN-COV2, a “cocktail” of two neutralizing antibodies that has shown promise in some animal studies (see here and here). The media jumped on an association between REGN-COV2 antibodies and fetal cells, some even claiming that the antibodies were developed from fetal cells.

 

Screenshot of NYT headline on Oct. 8, 2020

 

 

 

 

The fact of the matter is REGN-COV2 was tested for its virus-neutralizing ...read more