Transgenic Monkeys: Coming to a Lab Near You?

Blog, China, Emerging Technologies, Genomic & Genetics Issues, United States / /

D. Joy Riley, M.D., M.A. Executive Director

The initial draft sequence of the chimpanzee genome was published in September 2005 – in comparison with the human genome. A few months later, geneticist James M. Sikela wrote in PLOS Genetics, “the genes and genetic changes that are responsible for making the human brain what it is and for allowing it to do what it uniquely does, have long been among the most prized jewels of our genome.” In that paper, Sikela considered how one could locate the changes in the genome that account for “human-specific cognitive abilities.” How could one prove that a ...read more

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What Say You?

Blog, United States / /

Update: See the bottom of this post for the National Institutes of Health’s response to our letter. 

An Open Letter to Dr. Francis S. Collins, Director of the National Institutes of Health

D. Joy Riley, M.D., M.A. Executive Director

Francis S. Collins, M.D., Ph.D. Director National Institutes of Health 9000 Rockville Pike Bethesda, Maryland 20892 [email protected]

17 December 2018

Dear Dr. Collins:

The Tennessee Center for Bioethics & Culture lauds the position of the National Institutes of Health (NIH) as evidenced by your concluding statement of 28 November 2018: “NIH does not support the use of gene-editing technologies in human embryos.” As embryonic humans represent the most vulnerable amongst our species, the ...read more

What Say You? Read More »

What if we call it “Medical Aid in Dying”?

Blog, United States / /

 

A Lesson from History

In the aftermath of WWII, Leo Alexander penned the following as part of an article published in the New England Journal of Medicine:

The Example of Successful Resistance by the Physicians of the Netherlands There is no doubt that in Germany itself the first and most effective step of propaganda within the medical profession was the propaganda barrage against the useless, incurably sick described above. Similar, even more subtle efforts were made in some of the occupied countries. It is to the everlasting honor of the medical profession of Holland that they recognized the earliest and most subtle ...read more

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How Do We Promote Human Dignity?

Blog, United States / /

D. Joy Riley, M.D., M.A. Executive Director

A week ago, I was privileged to tour portions of a few of the buildings in a complex that had previously been used as a state “Hospital for the Insane” in Michigan. Although a number of the buildings have been repurposed into condos, restaurants, and shops, the two-hour tour was of several spaces that have yet to be restored. The architect of the original hospital and treatment regimen was a psychiatrist named Thomas Kirkbride. I was impressed by his understanding of human dignity, as represented by his work. The story is fascinating . . .

Thomas ...read more

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The ACP Releases a Position Paper on Physician-Assisted Suicide

Blog, End of Life, United States / /

D. Joy Riley, M.D., M.A. Executive Director

On 19 September 2017, the Ethics, Professionalism and Human Rights Committee of the American College of Physicians released their position paper on physician-assisted suicide (P-AS). A brief synopsis of it follows…

Re: Ethics and the Legalization of Physician-Assisted Suicide: An American College of Physicians Position Paper

The statement released last week builds on previous work:

1997 report by the Institute of Medicine (IOM), Approaching Death: Improving Care at the End of Life, which cited “inadequate end-of-life care” in the U.S. 2001 statement by the American College of Physicians, in which the ACP did not support the legalization of P-AS. ...read more

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It Has Arrived: Gene Editing Recommendations Published

Blog, Emerging Technologies, Engineering Humans, Genomic & Genetics Issues, United States / /

D. Joy Riley, M.D., M.A. Executive Director

The committee appointed to advise our government regarding the editing of genes, including editing the genes of the human embryo, has published a draft report (see the title page screen shot above). We at The Tennessee Center for Bioethics & Culture are studying the document’s 261 pages, and have a few caveats to share with our readers. Germline gene editing was given cautious approval by the committee:

Heritable germline genome editing trials must be approached with caution, but caution does not mean they must be prohibited. (p. 102)

and

If the technical challenges are ...read more

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CRISPR — Who’s in Charge? (Part IV)

Blog, Emerging Technologies, Engineering Humans, Genomic & Genetics Issues, United States / /

D. Joy Riley, M.D., M.A. Executive Director

This is part IV of our report. View part I, part II, or part III.

The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.

Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.

Here is a brief look at some of the writings and organizational ...read more

CRISPR — Who’s in Charge? (Part IV) Read More »

CRISPR — Who’s in Charge? (Part III)

Blog, Emerging Technologies, Engineering Humans, Genomic & Genetics Issues, United States / /

D. Joy Riley, M.D., M.A. Executive Director

This is part III of our report. View part I, part II, or part IV.

The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.

Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.

Here is a brief look at some of the writings and organizational ...read more

CRISPR — Who’s in Charge? (Part III) Read More »

CRISPR — Who’s in Charge? (Part II)

Blog, Emerging Technologies, Engineering Humans, Genomic & Genetics Issues, United States / /

D. Joy Riley, M.D., M.A. Executive Director

This is part II of our report. View part I, part III, or part IV.

The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.

Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.

Here is a brief look at some of the writings and organizational ...read more

CRISPR — Who’s in Charge? (Part II) Read More »