Seeing Patients Through Medical AI

Blog, C. Ben Mitchell, Emerging Technologies, Medicine & Health, uncategorized / /

C. Ben Mitchell, Ph.D.

Distinguished Fellow

The Tennessee Center for Bioethics & Culture

Artificial Intelligence (AI) is being integrated within the practice of medicine in leaps and bounds. Fields such as radiology, telehealth, and emergency medicine are increasingly implementing AI in diagnostics and treatment. Doubtless, AI will eventually enhance patient care, prognostics, and clinical practice generally. But at what cost to the physician-patient relationship and trust?

Keeping the patient in view as a whole person is already a challenge for contemporary medicine. Patients are often objectified by their body parts, disease, or location. “That’s the ovarian cancer in ...read more

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EctoLife: A Cautionary Tale

Blog, Emerging Technologies, Engineering Humans, Other Voices / /

 

Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University

In the December 2022 TN-CBC newsletter article entitled Déjà vu all over again, D. Joy Riley drew our attention to the parallels between the recently released YouTube video EctoLife: The world’s first artificial womb facility, and the fake publicity for the movie GATTACA 25 years ago. The new video, while actually conceptual, presents ectogenesis, the complete development of a baby in an artificial womb, as a current reality. Once again, a number of viewers were fooled. Unfortunately, it is perhaps more realistic than we dare to think. In a revealing interview by Beau Davidson with the Ectolife ...read more

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Déjà vu all over again

Blog, Emerging Technologies / /

By D. Joy Riley, M.D., M.A. Executive Director

The past couple of weeks have reminded me of the quote attributed to Yogi Berra, “It\’s Deja Vu All Over Again.”

Twenty-five years ago, the film, Gattaca, was released. One of the fake ads for the movie is pictured here. Thousands of people responded to the advertisements for the film, thinking it was the real deal.

In the past two weeks, multiple people have sent me the link to a new video, EctoLife: Concept Unveiled for the World’s First Artificial Womb Facility. Some are concerned that this is happening now; comments found online show a significant ...read more

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GATTACA: 25 Years On

Blog, Born Human, Emerging Technologies / /

Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University

(Editor’s Note: The Tennessee Center for Bioethics & Culture screened GATTACA at the end of June at the international bioethics conference held by the Center for Bioethics & Human Dignity at Trinity International University. Dr. Shelton presented opening remarks, which, lightly edited, are presented here.)

The movie, GATTACA, is entertaining to watch as is, but is also rife with symbolism and subtle—and some not so subtle—philosophical messages. 25 years on: it has proved to be prescient in a number of ways.

GATTACA depicts a dystopian world in which there is a new type of social ...read more

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A Moratorium on Heritable Human Genome Editing: Illusory or Real?

Blog, Emerging Technologies, Engineering Humans, Genomic & Genetics Issues / /

D. Joy Riley, M.D., M.A. Executive Director

In March, 2019, Nature published a commentary penned by Eric Lander, Françoise Baylis, Feng Zhang, Emmanuelle Charpentier, and Paul Berg, and signed by 13 other notables. The name of the commentary is “Adopt a moratorium on heritable genome editing.” This document requires analysis.

First, some definitions are needed. A moratorium is defined as a “suspension of activity,” or “an authorized period of delay or waiting.” Heritable means “capable of being passed from one generation to the next.” Additionally, clinical can refer to a “scientifically detached” attitude or “the observation and treatment of patients directly.” Each of ...read more

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Transgenic Monkeys: Coming to a Lab Near You?

Blog, China, Emerging Technologies, Genomic & Genetics Issues, United States / /

D. Joy Riley, M.D., M.A. Executive Director

The initial draft sequence of the chimpanzee genome was published in September 2005 – in comparison with the human genome. A few months later, geneticist James M. Sikela wrote in PLOS Genetics, “the genes and genetic changes that are responsible for making the human brain what it is and for allowing it to do what it uniquely does, have long been among the most prized jewels of our genome.” In that paper, Sikela considered how one could locate the changes in the genome that account for “human-specific cognitive abilities.” How could one prove that a ...read more

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First Human Embryos Edited in U.S.: A Bright Red Line Is Crossed

Blog, Emerging Technologies, Genomic & Genetics Issues, Medicine & Health, uncategorized, United States / /

D. Joy Riley, M.D., M.A. Executive Director

“Sooner than we expected”: A friend – a scientist steeped in the bioethics realm – wrote to me of her surprise at the announcement of the first embryonic humans edited in the United States. Steve Connor, writing in the MIT Technology Review, reported the work on 26 July 2017.  Doubtless, the publication of the work in a scientific journal will follow.

The article, “First human embryos edited in U.S.” by Steve Connor, describes the process thusly: “A person familiar with the research says ‘many tens’ of human IVF embryos were created for the experiment using the ...read more

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What Is a SHEEF, and Why Should We Care?

Blog, Emerging Technologies, Stem Cell Research, United States / /

D. Joy Riley, M.D., M.A. Executive Director

Human embryo research has long been guided by what is known as the “14-day rule.” That is, various nations have allowed research on embryos up to 14 days post fertilization. The 14-day rule was put in place ostensibly in order to avoid causing pain for the developing embryo. The primitive streak — the first visible evidence of gastrulation and the formation of differentiated tissues in the embryo — appears at about day 15 after fertilization. (See video at the bottom of this post for more information.)

When the 14-day rule was put in place, laboratories were ...read more

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It Has Arrived: Gene Editing Recommendations Published

Blog, Emerging Technologies, Engineering Humans, Genomic & Genetics Issues, United States / /

D. Joy Riley, M.D., M.A. Executive Director

The committee appointed to advise our government regarding the editing of genes, including editing the genes of the human embryo, has published a draft report (see the title page screen shot above). We at The Tennessee Center for Bioethics & Culture are studying the document’s 261 pages, and have a few caveats to share with our readers. Germline gene editing was given cautious approval by the committee:

Heritable germline genome editing trials must be approached with caution, but caution does not mean they must be prohibited. (p. 102)

and

If the technical challenges are ...read more

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CRISPR — Who’s in Charge? (Part IV)

Blog, Emerging Technologies, Engineering Humans, Genomic & Genetics Issues, United States / /

D. Joy Riley, M.D., M.A. Executive Director

This is part IV of our report. View part I, part II, or part III.

The ability to edit genes using CRISPR (clustered regularly interspaced short palindromic repeats) has been in the news for more than a year. A committee has been appointed to advise our government regarding the editing of genes, particularly editing the genes of the human embryo.

Who are the members of that committee? What are their views? The Tennessee Center for Bioethics & Culture has been working to gather information for you, our readers.

Here is a brief look at some of the writings and organizational ...read more

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