Life and Choice
Janet Liljestrand, M.D., M.A.
In 1862 Louis Pasteur performed the definitive experiment that proved even the smallest organisms, those only seen under the microscope, derived from other like organisms. (1) Life came from life. Fast forward to 1973, and Justice Blackmun, writing for the majority decision in Roe v. Wade stated “We need not resolve the difficult decision of when life begins”. (2) What was the Justice’s definition of life? The human zygote contains all it needs for cellular division–and thus growth–at the union of a living sperm and living egg. How then has its human life not begun? Yes, in ...read more
Guinea Pigs
Joyce A. Shelton, Ph.D. Professor of Biology Emerita Trinity International University
Successful xenotransplantation, animal donor to human recipient organ transfer, is the holy grail for medical doctors and scientists who study organ transplant. Why? Approximately 107,000 people are awaiting organ transplant in the US. Most will wait up to 2 to 3 years. About 17 people die per day because there are not enough organs available to meet the demand (1). Animal organs that have been genetically engineered to remove tissue molecules that cause transplant rejection would go a long way toward relieving the organ shortage.
A recently proclaimed major transplantation breakthrough attracted widespread ...read more
The Ethics of Rationing COVID-19 Vaccine for the Sickest Among Us
C. Ben Mitchell, Ph.D Distinguished Fellow
We must not allow our combined COVID-19 fatigue to prevent us from asking important questions about public health ethics. At the time I am writing this essay, we are just transitioning into Phase 2 of the vaccination plan. I am sure our public health officials are doing the best they can under unprecedented circumstances, so we should give them the benefit of the doubt. But for the sake of clarity in the future, some retrospective analysis will be crucial.
For instance, in our own state, we have abandoned traditional triage ethics in favor of a purely age-based ...read more
The Prescription for Flourishing Embodiment in Public Bioethics
A Book Review
C. Ben Mitchell, Ph.D. Distinguished Fellow
American public bioethics does not have a sterling history because it misunderstands its most important subject, the human subject. This is the claim of a brilliant new book by O. Carter Snead, the Director of the de Nicola Center for Ethics and Culture and professor of Political Science at the University of Notre Dame.
In What it Means to be Human: The Case for the Body in Public Bioethics (Harvard, 2020), Snead offers a genealogy of American public bioethics. Public bioethics, as contrasted with clinical bioethics, is the realm of human subjects research where, instead ...read more
The Problem of Ill-Gotten Gain in Health Care
C. Ben Mitchell, Ph.D. Distinguished Fellow
The politicized debate about President Trump’s treatment for Covid-19 may have shrouded an important set of questions about the science of developing treatments, viz., the problem of ill-gotten gain.
Among other treatment protocols, the President received Regeneron’s REGN-COV2, a “cocktail” of two neutralizing antibodies that has shown promise in some animal studies (see here and here). The media jumped on an association between REGN-COV2 antibodies and fetal cells, some even claiming that the antibodies were developed from fetal cells.
Screenshot of NYT headline on Oct. 8, 2020
The fact of the matter is REGN-COV2 was tested for its virus-neutralizing ...read more
A Project for Our Time
D. Joy Riley, M.D., M.A. Executive Director
The responses to the COVID-19 pandemic have been by turns dramatic and disconcerting, and, at times, draconian. I read about Steve Reiter’s deplorable experience and his new project in a BreakPoint commentary in July, and he was kind enough to speak with me by telephone on 24 July.
Steve’s beloved wife, Elizabeth, had diagnoses of lupus and pulmonary hypertension, among other difficulties. She had had a lengthy hospitalization in 2014, but had recovered. Steve attributes her recovery to excellent medical care and the 24/7 presence of her family. She had a Hickman line placed, and Steve ...read more
Life Without Us?
By Jane Patton, Guest Columnist
It is not new that some people say that they do not want to bring children into the world. And, as far as the do’s and don’ts of being environmentally responsible, the carbon footprint of a single human being tops the list of avoidable behaviors. One presidential candidate even advocates abortion as a way to combat climate change. So, it may be okay to have one or two children. Any more than that and parents might be called selfish.
But, a growing movement is taking the idea of limiting births to the next level—preventing all births. Who ...read more
When Can Others Help Themselves to Our Organs?
D. Joy Riley, M.D., M.A. Executive Director
We have an opt-in organ donation system in the United States. That is, you have to say, “Yes,” to organ donation in order to donate. Opting in is very easy, and you can usually do that through your local Department of Motor Vehicles (DMV). Even those too young to vote can opt-in for organ donation. Why is this service available through the DMV? A few moments’ thought can yield an answer.
England has recently changed its law governing organ donation. The new “opt-out” law takes effect in 2020:
Everyone in England over the age of 18 will ...read moreA Moratorium on Heritable Human Genome Editing: Illusory or Real?
D. Joy Riley, M.D., M.A. Executive Director
In March, 2019, Nature published a commentary penned by Eric Lander, Françoise Baylis, Feng Zhang, Emmanuelle Charpentier, and Paul Berg, and signed by 13 other notables. The name of the commentary is “Adopt a moratorium on heritable genome editing.” This document requires analysis.
First, some definitions are needed. A moratorium is defined as a “suspension of activity,” or “an authorized period of delay or waiting.” Heritable means “capable of being passed from one generation to the next.” Additionally, clinical can refer to a “scientifically detached” attitude or “the observation and treatment of patients directly.” Each of ...read more
